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trans-4,5-epoxy-2(E)-Decenal

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Catalog No. T36508Cas No. 134454-31-2
Alias trans-4,5-epoxy-2(E)-Decenal, 3-(3-pentyloxiranyl)-2E-propenal

Polyunsaturated fatty acids such as arachidonate and linoeate, while essential to health maintenance, are subject to random peroxidation by ambient oxygen, resulting in fragmented and reactive decomposition products. One prominent autoxidation product of either trilinolein or arachidonic acid is trans-4,5-epoxy-2(E)-decenal. One prominent autoxidation product of either trilinolein or arachidonic acid is trans-4,5-epoxy-2(E)-decenal. This aldehyde is responsible for a pungent metallic flavor of decomposed lipids, with a detection threshold of 1.5 pg/l in air.[1] trans-4,5-epoxy-2(E)-Decenal also reacts with nucleophiles (lysine amino groups) on proteins, leading to loss of cell function and viability.[2] This reactive aldehyde is therefore a useful tool in elucidating the effects of peroxidative damage in experimental models.

trans-4,5-epoxy-2(E)-Decenal

trans-4,5-epoxy-2(E)-Decenal

😃Good
Catalog No. T36508Alias trans-4,5-epoxy-2(E)-Decenal, 3-(3-pentyloxiranyl)-2E-propenalCas No. 134454-31-2
Polyunsaturated fatty acids such as arachidonate and linoeate, while essential to health maintenance, are subject to random peroxidation by ambient oxygen, resulting in fragmented and reactive decomposition products. One prominent autoxidation product of either trilinolein or arachidonic acid is trans-4,5-epoxy-2(E)-decenal. One prominent autoxidation product of either trilinolein or arachidonic acid is trans-4,5-epoxy-2(E)-decenal. This aldehyde is responsible for a pungent metallic flavor of decomposed lipids, with a detection threshold of 1.5 pg/l in air.[1] trans-4,5-epoxy-2(E)-Decenal also reacts with nucleophiles (lysine amino groups) on proteins, leading to loss of cell function and viability.[2] This reactive aldehyde is therefore a useful tool in elucidating the effects of peroxidative damage in experimental models.
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1 mg$508 35 days
5 mg$2,198 35 days
10 mg$3,878 35 days
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Product Introduction

Bioactivity
Description
Polyunsaturated fatty acids such as arachidonate and linoeate, while essential to health maintenance, are subject to random peroxidation by ambient oxygen, resulting in fragmented and reactive decomposition products. One prominent autoxidation product of either trilinolein or arachidonic acid is trans-4,5-epoxy-2(E)-decenal. One prominent autoxidation product of either trilinolein or arachidonic acid is trans-4,5-epoxy-2(E)-decenal. This aldehyde is responsible for a pungent metallic flavor of decomposed lipids, with a detection threshold of 1.5 pg/l in air.[1] trans-4,5-epoxy-2(E)-Decenal also reacts with nucleophiles (lysine amino groups) on proteins, leading to loss of cell function and viability.[2] This reactive aldehyde is therefore a useful tool in elucidating the effects of peroxidative damage in experimental models.
Aliastrans-4,5-epoxy-2(E)-Decenal, 3-(3-pentyloxiranyl)-2E-propenal
Chemical Properties
Molecular Weight168.236
FormulaC10H16O2
Cas No.134454-31-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMF: 30 mg/mL (178.32 mM), Sonication is recommended.
Ethanol: 30 mg/mL (178.32 mM), Sonication is recommended.
DMSO: 30 mg/mL (178.32 mM), Sonication is recommended.
Solution Preparation Table
DMF/Ethanol/DMSO
1mg5mg10mg50mg
1 mM5.9440 mL29.7202 mL59.4403 mL297.2016 mL
5 mM1.1888 mL5.9440 mL11.8881 mL59.4403 mL
10 mM0.5944 mL2.9720 mL5.9440 mL29.7202 mL
20 mM0.2972 mL1.4860 mL2.9720 mL14.8601 mL
50 mM0.1189 mL0.5944 mL1.1888 mL5.9440 mL
100 mM0.0594 mL0.2972 mL0.5944 mL2.9720 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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