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tri-GalNAc biotin
tri-GalNAc biotin
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tri-GalNAc biotin
Catalog No. T77941
Tri-GalNAc biotin, a small molecule lysosome targeting degrader, serves as a ligand for the asialoglycoprotein receptor (ASGPR). It promotes the uptake of NeutrAvidin (NA) into liver cells via ASGPR and directs NeutrAvidin to the lysosome for degradation. This compound is applicable in the study of Lysosome Targeting Chimeras (LYTAC) [1].
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μg | $1,960 | 35 days |
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Tri-GalNAc(OAc)3-Perfluorophenyl
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Tri-GalNAc(OAc)3-Perfluorophenyl is a pentafluorophenyl-modified triantenerrary N-acetylgalactosamine (tri-GalNAc) ligand utilized in the synthesis of GalNAc-lysosome-targeting chimeras (LYTACs). These chimeras facilitate targeted protein degradation through engagement with the asialoglycoprotein receptor [1].
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TriGalNAc CBz
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TriGalNAc CBz is a GalNAc derivative. As an ASGPR ligand, tri-GalNAc targets lysosomes in mRNA drug delivery and LYTAC studies.L-DABA hydrobromide.
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Tri-GalNAc(OAc)3
T779461159408-64-6
Tri-GalNAc(OAc)3, a triantenerrary N-acetylgalactosamine (tri-GalNAc) ligand, is utilized in the synthesis of GalNAc-lysosome targeting chimeras (LYTAC). These chimeras exploit the asialoglycoprotein receptor to direct protein degradation targets to the lysosome [1].
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Tri-GalNAc(OAc)3 TFA
T779471159408-65-7
Tri-GalNAc(OAc)3 TFA, a triantenerrary N-acetylgalactosamine (tri-GalNAc) ligand, is utilized in the synthesis of GalNAc-lysosome-targeting chimera (GalNAc-LYTAC). This compound facilitates targeted protein degradation by engaging with the asialoglycoprotein receptor [1].
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Tri-GalNAc-NHS ester
T809461953146-83-2
Tri-GalNAc-NHS ester, a LYsosome TArgeting Chimera (LYTAC) and ligand for the asialoglycoprotein receptor (ASGPR), facilitates the degradation of extracellular proteins, including membrane proteins, via the lysosomal targeting receptor expressed on liver cells. This compound is utilized as a protein degrader in LYTAC research [1].
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tri-GalNAc-COOH (acetylation)
T80947
Tri-GalNAc-COOH acetylation represents the acetylated derivative of tri-galactosamine (tri-GalNAc-COOH), utilized in the synthesis of lysosome targeting chimeras (LYTAC).
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M-MoDE-A (2)
T817792378837-56-8
M-MoDE-A (2) is a bifunctional small molecule that facilitates the degradation of extracellular proteins via the asialoglycoprotein receptor (ASGPR).
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D-MoDE-A (1)
T825372378837-67-1
D-MoDE-A (1) is a bifunctional small molecule that facilitates extracellular protein degradation via the asialoglycoprotein receptor (ASGPR).
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tri-GalNAc-COOH
T393701953146-81-0In house
Tri-GalNAc-COOH is a ligand for the asialoglycoprotein receptor (ASGPR) commonly employed in Lysosome Targeting Chimera (LYTAC) investigations.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Tri-GalNAc biotin, a small molecule lysosome targeting degrader, serves as a ligand for the asialoglycoprotein receptor (ASGPR). It promotes the uptake of NeutrAvidin (NA) into liver cells via ASGPR and directs NeutrAvidin to the lysosome for degradation. This compound is applicable in the study of Lysosome Targeting Chimeras (LYTAC) [1]. |
| Molecular Weight | 1916.19 |
| Formula | C83H146N14O34S |
| Cas No. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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