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Trimethoprim 3-oxide

Name: Trimethoprim 3-oxide
Brand: TargetMol
SKU: T19593
Rating: 4.5 (1 reviews)

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Catalog No. T19593Cas No. 27653-67-4

Alias Trimethoprim 3-N-oxide

Trimethoprim 3-oxide trimethoprim primary metabolite.

Trimethoprim 3-oxide

😃Good

Catalog No. T19593Alias Trimethoprim 3-N-oxideCas No. 27653-67-4

Trimethoprim 3-oxide trimethoprim primary metabolite.

Pack Size	Price	Availability
25 mg	$1,520	2-4 weeks
50 mg	$1,980	2-4 weeks
100 mg	$2,500	2-4 weeks

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Product Introduction

Bioactivity

Description	Trimethoprim 3-oxide trimethoprim primary metabolite.
In vitro	In human liver microsomes (HLMs), Trimethoprim 3-oxide (3-NO-TMP) is converted from trimethoprim by CYP1A1 and CYP1B1 with highest rates. The inhibitor of CYP1A α-Naphthoflavone inhibits Trimethoprim 3-oxide formation
Alias	Trimethoprim 3-N-oxide

Chemical Properties

Molecular Weight	306.32
Formula	C₁₄H₁₈N₄O₄
Cas No.	27653-67-4
Relative Density.	1.36 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TrimethoprimTrimethoprim 3-oxideTrimethoprim 3oxideTrimethoprim 3 oxide