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Trimethoprim 3-oxide

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Catalog No. T19593Cas No. 27653-67-4
Alias Trimethoprim 3-N-oxide

Trimethoprim 3-oxide trimethoprim primary metabolite.

Trimethoprim 3-oxide
Other Forms of Trimethoprim 3-oxide:

Trimethoprim 3-oxide

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Catalog No. T19593Alias Trimethoprim 3-N-oxideCas No. 27653-67-4
Trimethoprim 3-oxide trimethoprim primary metabolite.
Pack SizePriceAvailabilityQuantity
25 mg$1,520 2-4 weeks
50 mg$1,980 2-4 weeks
100 mg$2,500 2-4 weeks
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Product Introduction

Bioactivity
Description
Trimethoprim 3-oxide trimethoprim primary metabolite.
In vitro
In human liver microsomes (HLMs), Trimethoprim 3-oxide (3-NO-TMP) is converted from trimethoprim by CYP1A1 and CYP1B1 with highest rates. The inhibitor of CYP1A α-Naphthoflavone inhibits Trimethoprim 3-oxide formation
AliasTrimethoprim 3-N-oxide
Chemical Properties
Molecular Weight306.32
FormulaC14H18N4O4
Cas No.27653-67-4
Relative Density.1.36 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

TrimethoprimTrimethoprim 3-oxideTrimethoprim 3oxideTrimethoprim 3 oxide
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