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Tryptoquivaline D
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Catalog No. T37584Cas No. 60676-56-4
Tryptoquivaline D is a fungal metabolite found in [Neosartorya siamensis] with noted anticancer activity. It induces nuclear chromatin condensation, a marker of apoptosis, in HCT116 colon and HepG2 liver cancer cells at a concentration of 150 μM. Tryptoquivaline D (1-100 μM), alone or with doxorubicin, reduces the viability of A549 lung cancer cells.
Tryptoquivaline D
😃Good
Catalog No. T37584Cas No. 60676-56-4
Tryptoquivaline D is a fungal metabolite found in [Neosartorya siamensis] with noted anticancer activity. It induces nuclear chromatin condensation, a marker of apoptosis, in HCT116 colon and HepG2 liver cancer cells at a concentration of 150 μM. Tryptoquivaline D (1-100 μM), alone or with doxorubicin, reduces the viability of A549 lung cancer cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 846 € | Backorder |
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Bioactivity
Chemical Properties
| Description | Tryptoquivaline D is a fungal metabolite found in [Neosartorya siamensis] with noted anticancer activity. It induces nuclear chromatin condensation, a marker of apoptosis, in HCT116 colon and HepG2 liver cancer cells at a concentration of 150 μM. Tryptoquivaline D (1-100 μM), alone or with doxorubicin, reduces the viability of A549 lung cancer cells. |
| Molecular Weight | 532.553 |
| Formula | C28H28N4O7 |
| Cas No. | 60676-56-4 |
| Relative Density. | 1.52 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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