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TSHR antagonist S37b

Name: TSHR antagonist S37b
Brand: TargetMol
SKU: T38226
Rating: 4.5 (1 reviews)

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Catalog No. T38226Cas No. 2143452-22-4

TSHR antagonist S37b, the less potent enantiomer of TSHR antagonist S37a, exhibits minimal efficacy in inhibiting the thyrotropin receptor (TSHR). It is utilized in thyroid function research[1].

TSHR antagonist S37b

😃Good

Catalog No. T38226Cas No. 2143452-22-4

TSHR antagonist S37b, the less potent enantiomer of TSHR antagonist S37a, exhibits minimal efficacy in inhibiting the thyrotropin receptor (TSHR). It is utilized in thyroid function research[1].

Pack Size	Price	Availability
5 mg	$476	6-8 weeks
25 mg	$1,530	6-8 weeks
50 mg	$1,990	6-8 weeks
100 mg	$2,980	6-8 weeks

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Product Introduction

Bioactivity

Description

TSHR antagonist S37b, the less potent enantiomer of TSHR antagonist S37a, exhibits minimal efficacy in inhibiting the thyrotropin receptor (TSHR). It is utilized in thyroid function research[1].

Chemical Properties

Molecular Weight	460.57
Formula	C₂₅H₂₀N₂O₃S₂
Cas No.	2143452-22-4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 100 mg/mL (217.12 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1712 mL	10.8561 mL	21.7122 mL	108.5611 mL
5 mM	0.4342 mL	2.1712 mL	4.3424 mL	21.7122 mL
10 mM	0.2171 mL	1.0856 mL	2.1712 mL	10.8561 mL
20 mM	0.1086 mL	0.5428 mL	1.0856 mL	5.4281 mL
50 mM	0.0434 mL	0.2171 mL	0.4342 mL	2.1712 mL
100 mM	0.0217 mL	0.1086 mL	0.2171 mL	1.0856 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TSHR antagonist S37bTSHR antagonist S-37b