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Tuberculosis inhibitor 3

Name: Tuberculosis inhibitor 3
Brand: TargetMol
SKU: T38298
Rating: 4.5 (1 reviews)

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Catalog No. T38298Cas No. 2219325-28-5

Tuberculosis inhibitor 3 (compound 2i) exhibits potent anti-TB properties (MIC < 0.016 μg/mL) against both drug-sensitive and resistant MTB strains, with acceptable pharmacokinetic profiles and oral bioavailability[1].

Tuberculosis inhibitor 3

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Catalog No. T38298Cas No. 2219325-28-5

Pack Size	Price	Availability
2 mg	$113	5 days
5 mg	$187	5 days
25 mg	$626	6-8 weeks
50 mg	$814	6-8 weeks
100 mg	$1,190	6-8 weeks

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Tuberculosis inhibitor 3 (compound 2i) exhibits potent anti-TB properties (MIC < 0.016 μg/mL) against both drug-sensitive and resistant MTB strains, with acceptable pharmacokinetic profiles and oral bioavailability[1].
In vitro	Tuberculosis inhibitor 3 (compound 2i, 50 mg/kg) exhibits acceptable pharmacokinetic properties, with an AUC of 2489 h ng/mL and a Tmax of 0.25 h[1].

Chemical Properties

Molecular Weight	524.48
Formula	C₂₁H₂₂F₆N₄O₃S
Cas No.	2219325-28-5
Relative Density.	1.60 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 27.5 mg/mL (52.43 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9067 mL	9.5333 mL	19.0665 mL	95.3325 mL
5 mM	0.3813 mL	1.9067 mL	3.8133 mL	19.0665 mL
10 mM	0.1907 mL	0.9533 mL	1.9067 mL	9.5333 mL
20 mM	0.0953 mL	0.4767 mL	0.9533 mL	4.7666 mL
50 mM	0.0381 mL	0.1907 mL	0.3813 mL	1.9067 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Tuberculosis inhibitor 3