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Tubulinpolymer-in-44 (compound 7w) inhibits Tubulin with an IC50 of 0.21 μM and induces apoptosis by arresting the G2/M phase, making it useful for cancer research.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | Tubulinpolymer-in-44 (compound 7w) inhibits Tubulin with an IC50 of 0.21 μM and induces apoptosis by arresting the G2/M phase, making it useful for cancer research. |
In vitro | Tubulin Polymerization Inhibitor-44 (0.42 μM, 24-48 h) exhibits robust anti-proliferative activity against SGC-7910 cells with an IC50 of 0.21 μM. |
In vivo | Tubulin polymers-in-44, at dosages ranging from 5-20 mg/kg administered every other day, can inhibit tumor growth in a 4T1 breast cancer mouse model without causing weight loss. |
Molecular Weight | 436.31 |
Formula | C19H15Cl2N3O3S |
Storage | Shipping with blue ice. |
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