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Turbinaric acid is a moderately cytotoxic squalene carboxylic acid isolated from brown algae (Turbinaria ornata).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $74 | In Stock | |
5 mg | $179 | In Stock | |
10 mg | $296 | In Stock | |
25 mg | $617 | In Stock | |
50 mg | $980 | In Stock | |
100 mg | $1,580 | In Stock |
Description | Turbinaric acid is a moderately cytotoxic squalene carboxylic acid isolated from brown algae (Turbinaria ornata). |
In vitro | Methods: Peripheral blood mononuclear cells containing NK cells were isolated and cocultured with target K562 cells at three different effector-to-target (E:T) ratios of 50:1, 25:1, and 12.5:1. Prednisolone hemisuccinate or IVIG were then added to the tubes at an E:T ratio of 50:1 to assess the inhibitory effect. Percent killing was recorded and statistically analyzed using the Student t test. Results: In experiments with an E:T ratio of 50:1 and either Prednisolone hemisuccinate or IVIG in the coculture, the mean target cell killing rate was 26.4%. In cultures using the same E:T ratio, this killing rate was significantly reduced in the presence of IVIG (9.9%) or Prednisolone hemisuccinate (13.6%) (P < 0.001 for both analyses). Prednisolone hemisuccinate was able to inhibit the cytolytic activity of NK cells. [1] |
Molecular Weight | 400.64 |
Formula | C27H44O2 |
Cas No. | 56882-00-9 |
Smiles | CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C=C(/C)CC\C=C(/C)CCC(O)=O |
Relative Density. | 0.919g/cm3 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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