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U-74389G

Name: U-74389G
Brand: TargetMol
SKU: T36509
Rating: 4.5 (1 reviews)

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Catalog No. T36509Cas No. 153190-29-5

Alias U-74389G, Methylated Tirilazad

U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It protects against ischemia-reperfusion injury in animal heart, liver, and kidney models.[1],[2],[3],[4]

U-74389G

😃Good

Catalog No. T36509Alias U-74389G, Methylated TirilazadCas No. 153190-29-5

U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It protects against ischemia-reperfusion injury in animal heart, liver, and kidney models.[1],[2],[3],[4]

Pack Size	Price	Availability
50 mg	$180	35 days
100 mg	$288	35 days
250 mg	$665	35 days

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It protects against ischemia-reperfusion injury in animal heart, liver, and kidney models.[1],[2],[3],[4]
Alias	U-74389G, Methylated Tirilazad

Chemical Properties

Molecular Weight	726.919
Formula	C₄₁H₅₄N₆O₆
Cas No.	153190-29-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 35 mg/mL (48.15 mM), Sonication is recommended.

DMF: 36 mg/mL (49.52 mM), Sonication is recommended.

Ethanol: 1 mg/mL (1.38 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
1 mM	1.3757 mL	6.8783 mL	13.7567 mL	68.7835 mL

DMSO/DMF

	1mg	5mg	10mg	50mg
5 mM	0.2751 mL	1.3757 mL	2.7513 mL	13.7567 mL
10 mM	0.1376 mL	0.6878 mL	1.3757 mL	6.8783 mL
20 mM	0.0688 mL	0.3439 mL	0.6878 mL	3.4392 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

U74389GU 74389G