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Vibegron

Catalog No. T35052Cas No. 1190389-15-1
Alias MK-4618, MK4618, MK 4618

Vibegron (MK-4618) is an effective and selective Beta 3 adrenergic receptor agonist, used to treat overactive bladder (OAB).

Vibegron

Vibegron

Catalog No. T35052Alias MK-4618, MK4618, MK 4618Cas No. 1190389-15-1
Vibegron (MK-4618) is an effective and selective Beta 3 adrenergic receptor agonist, used to treat overactive bladder (OAB).
Pack SizePriceAvailabilityQuantity
25 mg$2,57010-14 weeks
50 mg$3,38010-14 weeks
100 mg$4,60010-14 weeks
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Product Introduction

Bioactivity
Description
Vibegron (MK-4618) is an effective and selective Beta 3 adrenergic receptor agonist, used to treat overactive bladder (OAB).
Targets&IC50
β3-adrenoceptor:1.1 nM (EC50)
AliasMK-4618, MK4618, MK 4618
Chemical Properties
Molecular Weight444.53
FormulaC26H28N4O3
Cas No.1190389-15-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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