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VRK-IN-1

Name: VRK-IN-1
Brand: TargetMol
SKU: T35863
Price: 114 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T35863Cas No. 2378855-09-3

VRK-IN-1 is a potent and selective inhibitor of [cowpox-associated kinase 1 (VRK1)], suitable for researching neurological disorders.

VRK-IN-1

🥰Excellent

Purity: 99.25%

Catalog No. T35863Cas No. 2378855-09-3

VRK-IN-1 is a potent and selective inhibitor of [cowpox-associated kinase 1 (VRK1)], suitable for researching neurological disorders.

Pack Size	Price	Availability
1 mg	$114	In Stock
5 mg	$249	In Stock
10 mg	$398	In Stock
25 mg	$789	In Stock
50 mg	$1,198	In Stock
1 mL x 10 mM (in DMSO)	$274	In Stock

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Purity:99.25%

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COA LCMS

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	VRK-IN-1 is a potent and selective inhibitor of [cowpox-associated kinase 1 (VRK1)], suitable for researching neurological disorders.
Targets&IC50	VRK1:150 nM (IC50), VRK1:150 nM
In vitro	VRK-IN-1 (3.2 μM; 24 hours) slightly decreases the viability of human HeLa cells[1].

Chemical Properties

Molecular Weight	349.28
Formula	C₁₈H₁₁F₄NO₂
Cas No.	2378855-09-3
Smiles	Cc1ncc(cc1-c1cc(F)c(O)c(F)c1)-c1cc(F)c(O)c(F)c1
Relative Density.	1.436 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 80 mg/mL (229.04 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8630 mL	14.3152 mL	28.6303 mL	143.1516 mL
5 mM	0.5726 mL	2.8630 mL	5.7261 mL	28.6303 mL
10 mM	0.2863 mL	1.4315 mL	2.8630 mL	14.3152 mL
20 mM	0.1432 mL	0.7158 mL	1.4315 mL	7.1576 mL
50 mM	0.0573 mL	0.2863 mL	0.5726 mL	2.8630 mL
100 mM	0.0286 mL	0.1432 mL	0.2863 mL	1.4315 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

VRK-IN-1VRKIN1VRK IN 1