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WWL113

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Catalog No. T17259Cas No. 947669-86-5

WWL113 is a selective and orally active inhibitor of Ces3 (IC50: 120 nM) and Ces1f (IC50: 100 nM), exhibiting excellent selectivity for the 60-kDa serine hydrolase.

WWL113

WWL113

😃Good
Catalog No. T17259Cas No. 947669-86-5
WWL113 is a selective and orally active inhibitor of Ces3 (IC50: 120 nM) and Ces1f (IC50: 100 nM), exhibiting excellent selectivity for the 60-kDa serine hydrolase.
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2 mg$505 days
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Product Introduction

Bioactivity
Description
WWL113 is a selective and orally active inhibitor of Ces3 (IC50: 120 nM) and Ces1f (IC50: 100 nM), exhibiting excellent selectivity for the 60-kDa serine hydrolase.
Targets&IC50
Ces1f:100 nM, Ces3:120 nM
Chemical Properties
Molecular Weight466.53
FormulaC29H26N2O4
Cas No.947669-86-5
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

WWL-113WWL113WWL 113Ces3Ces1f
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