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X77

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Catalog No. T9671Cas No. 2455518-33-7

X77 is an effective non-covalent inhibitor of the main protease of SARS-CoV-2 ( SARS-CoV-2 M pro ) [1]. X77 binds to SARS-CoV-2 M pro with a Kd value of 0.057 μM [2].

X77
Other Forms of X77:
(Rac)-X77T86882144491-78-9
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X77

😃Good
Catalog No. T9671Cas No. 2455518-33-7
X77 is an effective non-covalent inhibitor of the main protease of SARS-CoV-2 ( SARS-CoV-2 M pro ) [1]. X77 binds to SARS-CoV-2 M pro with a Kd value of 0.057 μM [2].
Pack SizePriceAvailabilityQuantity
2 mg221 €5 days
25 mg906 €6-8 weeks
50 mg1.178 €6-8 weeks
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Product Introduction

Bioactivity
Description
X77 is an effective non-covalent inhibitor of the main protease of SARS-CoV-2 ( SARS-CoV-2 M pro ) [1]. X77 binds to SARS-CoV-2 M pro with a Kd value of 0.057 μM [2].
In vitro
X77 binds to SARS-CoV-2 M protease (PDB code: 6W63), the main protease of SARS-CoV-2, which is a critical drug target among coronaviruses [1].
Chemical Properties
Molecular Weight459.58
FormulaC27H33N5O2
Cas No.2455518-33-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

X 77X77X-77
Related Tags: buy X77 | purchase X77 | X77 cost | order X77 | X77 chemical structure | X77 in vitro | X77 formula | X77 molecular weight
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