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YG1702

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Catalog No. T80755Cas No. 724737-08-0

YG1702, a potent inhibitor specific to ALDH18A1, suppresses the proliferation of MYCN-amplified neuroblastoma (NB) and reduces MYCN expression. This compound exhibits high-affinity physical interaction with ALDH18A1, which may influence its enzymatic activity [1].

YG1702

YG1702

😃Good
Catalog No. T80755Cas No. 724737-08-0
YG1702, a potent inhibitor specific to ALDH18A1, suppresses the proliferation of MYCN-amplified neuroblastoma (NB) and reduces MYCN expression. This compound exhibits high-affinity physical interaction with ALDH18A1, which may influence its enzymatic activity [1].
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5 mgInquiry8-10 weeks
50 mgInquiry8-10 weeks
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Product Introduction

Bioactivity
Description
YG1702, a potent inhibitor specific to ALDH18A1, suppresses the proliferation of MYCN-amplified neuroblastoma (NB) and reduces MYCN expression. This compound exhibits high-affinity physical interaction with ALDH18A1, which may influence its enzymatic activity [1].
In vivo
YG1702, administered intraperitoneally at a dosage of 45 mg/kg every three days for a total of three administrations, inhibited the growth of xenografts in tumor-bearing mice [1].
Chemical Properties
Molecular Weight478.56
FormulaC23H30N2O7S
Cas No.724737-08-0
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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