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The diazomethyl ketone Z-LVG-CHN2 mimics part of the human cysteine proteinase-binding center, has been shown to be an irreversible inhibitor of this proteinase. The compound was also tested for antiviral activity against herpes simplex virus type 1 (HSV) and found to block the HSV replication. Irreversible inhibitor of streptopain.
Description | The diazomethyl ketone Z-LVG-CHN2 mimics part of the human cysteine proteinase-binding center, has been shown to be an irreversible inhibitor of this proteinase. The compound was also tested for antiviral activity against herpes simplex virus type 1 (HSV) and found to block the HSV replication. Irreversible inhibitor of streptopain. |
Targets&IC50 | SAR CoV-2:190 nM (EC50) |
Alias | Z-Leu-Val-Gly-diazomethylketone |
Molecular Weight | 445.52 |
Formula | C22H31N5O5 |
Cas No. | 119670-30-3 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | Methanol: 50 mg/mL (112.23 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
Methanol
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