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Z-Phe-Tyr(tBu)-diazomethylketone

Name: Z-Phe-Tyr(tBu)-diazomethylketone
Brand: TargetMol
SKU: T35753
Rating: 4.5 (1 reviews)

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Catalog No. T35753Cas No. 114014-15-2

Irreversible cathepsin L inhibitor which is ca 10'000 times more effective in inactivating cathepsin L than cathepsin S.

Z-Phe-Tyr(tBu)-diazomethylketone

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Catalog No. T35753Cas No. 114014-15-2

Irreversible cathepsin L inhibitor which is ca 10'000 times more effective in inactivating cathepsin L than cathepsin S.

Pack Size	Price	Availability	Quantity
1 mg	Inquiry	35 days
5 mg	Inquiry	35 days

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description

Irreversible cathepsin L inhibitor which is ca 10'000 times more effective in inactivating cathepsin L than cathepsin S.

Chemical Properties

Molecular Weight	542.636
Formula	C₃₁H₃₄N₄O₅
Cas No.	114014-15-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

Ethyl Acetate: 10 mg/mL (18.43 mM), Sonication is recommended.

Solution Preparation Table

Ethyl Acetate

	1mg	5mg	10mg	50mg
1 mM	1.8429 mL	9.2143 mL	18.4286 mL	92.1428 mL
5 mM	0.3686 mL	1.8429 mL	3.6857 mL	18.4286 mL
10 mM	0.1843 mL	0.9214 mL	1.8429 mL	9.2143 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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