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Z-CITCO

Name: Z-CITCO
Brand: TargetMol
SKU: T83878
Rating: 4.5 (1 reviews)

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Catalog No. T83878Cas No. 2583138-04-7

Z-CITCO acts as an agonist for the constitutive androstane receptor (CAR; with an EC50 of 3.9 µM in human receptor reporter assays) and is the cis isomer of the CAR agonist CITCO.

Z-CITCO

😃Good

Catalog No. T83878Cas No. 2583138-04-7

Z-CITCO acts as an agonist for the constitutive androstane receptor (CAR; with an EC50 of 3.9 µM in human receptor reporter assays) and is the cis isomer of the CAR agonist CITCO.

Pack Size	Price	Availability
1 mg	Inquiry	35 days
5 mg	Inquiry	35 days
10 mg	Inquiry	35 days
25 mg	Inquiry	35 days

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Product Introduction

Bioactivity

Description

Z-CITCO acts as an agonist for the constitutive androstane receptor (CAR; with an EC50 of 3.9 µM in human receptor reporter assays) and is the cis isomer of the CAR agonist CITCO.

Chemical Properties

Molecular Weight	436.70
Formula	C₁₉H₁₂Cl₃N₃OS
Cas No.	2583138-04-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMF: 20 mg/mL (45.8 mM), Sonication is recommended.

DMSO: 10 mg/mL (22.9 mM), Sonication is recommended.

Solution Preparation Table

DMSO/DMF

	1mg	5mg	10mg	50mg
1 mM	2.2899 mL	11.4495 mL	22.8990 mL	114.4951 mL
5 mM	0.4580 mL	2.2899 mL	4.5798 mL	22.8990 mL
10 mM	0.2290 mL	1.1450 mL	2.2899 mL	11.4495 mL
20 mM	0.1145 mL	0.5725 mL	1.1450 mL	5.7248 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc