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Zilovertamab
🥰Excellent
Catalog No. T76749Cas No. 1643432-38-5
Alias UC-961, Cirmtuzumab
Zilovertamab (UC-961) is a humanized anti-ROR1 monoclonal antibody that cuts off the WNT5A-induced ROR1 signaling pathway and shows anti-proliferative activity in ovarian and endometrial cancer cells. It can be used to study lymphatic cancer.
Zilovertamab
Zilovertamab
🥰Excellent
Catalog No. T76749Alias UC-961, CirmtuzumabCas No. 1643432-38-5
Zilovertamab (UC-961) is a humanized anti-ROR1 monoclonal antibody that cuts off the WNT5A-induced ROR1 signaling pathway and shows anti-proliferative activity in ovarian and endometrial cancer cells. It can be used to study lymphatic cancer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $247 | In Stock | |
| 5 mg | $690 | In Stock | |
| 10 mg | $1,120 | In Stock | |
| 25 mg | $1,660 | In Stock | |
| 50 mg | $2,230 | In Stock | |
| 100 mg | $2,950 | In Stock |
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Concentration:21.48 mg/mL
Purity:> 95%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Zilovertamab (UC-961) is a humanized anti-ROR1 monoclonal antibody that cuts off the WNT5A-induced ROR1 signaling pathway and shows anti-proliferative activity in ovarian and endometrial cancer cells. It can be used to study lymphatic cancer. |
| In vitro | Zilovertamab (25 and 50 µg/mL; 72 h) inhibits the proliferation of high-grade serous ovarian cancer (HGSOC) cells[1]. Zilovertamab (50 µg/mL; 72 h) down-regulates the expression levels of ROR1 in CaOV3 at the transcriptional level[1]. |
| Alias | UC-961, Cirmtuzumab |
| Molecular Weight | 145.12 kDa |
| Cas No. | 1643432-38-5 |
Storage & Solubility Information
| Storage | store at low temperature | store at -80°C | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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