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ZJ-101

Catalog No. T87673Cas No. 1448446-23-8

ZJ-101, a structurally simplified analog of the marine natural product superstolide A, exhibits potent antiproliferative activity by targeting and inhibiting O-glycosylation, thereby modulating the endomembrane system and inhibiting cell-cell adhesion [1].

ZJ-101

ZJ-101

Catalog No. T87673Cas No. 1448446-23-8
ZJ-101, a structurally simplified analog of the marine natural product superstolide A, exhibits potent antiproliferative activity by targeting and inhibiting O-glycosylation, thereby modulating the endomembrane system and inhibiting cell-cell adhesion [1].
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Product Introduction

Bioactivity
Description
ZJ-101, a structurally simplified analog of the marine natural product superstolide A, exhibits potent antiproliferative activity by targeting and inhibiting O-glycosylation, thereby modulating the endomembrane system and inhibiting cell-cell adhesion [1].
In vitro
ZJ-101 exhibits antiproliferative effects against MCF-7, MDA-MB-231, and HCT-116 cell lines, with IC 50 values of 40.8 nM (MCF-7), 61.1 nM (MDA-MB-231), and 88.2 nM (HCT-116) [1].
Chemical Properties
Molecular Weight481.67
FormulaC30H43NO4
Cas No.1448446-23-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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