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Zotiraciclib HCl

Catalog No. T70897Cas No. 1354567-82-0

Zotiraciclib, also known as TG02 and SB1317, is a novel small molecule potent CDK/JAK2/FLT3 inhibitor. Zotiraciclib may be useful for the treatment of cancer that crosses the blood brain barrier and acts by depleting Myc through the inhibition of cyclin-dependent kinase 9 (CDK9). It is one of a number of CDK inhibitors under investigation; others targeting CDK9 for the treatment of acute myeloid leukemia include alvocidib and atuveciclib. Myc overexpression is a known factor in many cancers, with 80 percent of glioblastomas characterized by this property.

Zotiraciclib HCl
Other Forms of Zotiraciclib HCl:
(E/Z)-Zotiraciclib hydrochlorideT620561321626-25-8
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(E/Z)-ZotiraciclibT21503937270-47-8
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(E/Z)-Zotiraciclib citrateT63998
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Zotiraciclib HCl

Catalog No. T70897Cas No. 1354567-82-0
Zotiraciclib, also known as TG02 and SB1317, is a novel small molecule potent CDK/JAK2/FLT3 inhibitor. Zotiraciclib may be useful for the treatment of cancer that crosses the blood brain barrier and acts by depleting Myc through the inhibition of cyclin-dependent kinase 9 (CDK9). It is one of a number of CDK inhibitors under investigation; others targeting CDK9 for the treatment of acute myeloid leukemia include alvocidib and atuveciclib. Myc overexpression is a known factor in many cancers, with 80 percent of glioblastomas characterized by this property.
Pack SizePriceAvailabilityQuantity
25 mg$1,6706-8 weeks
50 mg$2,1806-8 weeks
100 mg$2,8006-8 weeks
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Product Introduction

Bioactivity
Description
Zotiraciclib, also known as TG02 and SB1317, is a novel small molecule potent CDK/JAK2/FLT3 inhibitor. Zotiraciclib may be useful for the treatment of cancer that crosses the blood brain barrier and acts by depleting Myc through the inhibition of cyclin-dependent kinase 9 (CDK9). It is one of a number of CDK inhibitors under investigation; others targeting CDK9 for the treatment of acute myeloid leukemia include alvocidib and atuveciclib. Myc overexpression is a known factor in many cancers, with 80 percent of glioblastomas characterized by this property.
Chemical Properties
Molecular Weight445.388
FormulaC23H26Cl2N4O
Cas No.1354567-82-0
Storage & Solubility Information
StorageShipping with blue ice.

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Keywords

4SC-101IMU838SC-12267IMU-838Zotiraciclib HClIM-90838VidofludimusIM90838IMU 8384SC101SC12267SC 122674SC 101IM 90838
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