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APS-2-79

Catalog No. T70004Cas No. 2002381-25-9

APS-2-79, a KSR-dependent MEK antagonist, disrupts ATP (biotin) binding within the KSR2-MEK1 complex, achieving an inhibitory concentration (IC50) of 120 nM. This action stabilizes the KSR inactive state and antagonizes oncogenic Ras-MAPK signaling.

APS-2-79
Other Forms of APS-2-79:
APS-2-79 hydrochlorideT67602002381-31-7
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APS-2-79

Catalog No. T70004Cas No. 2002381-25-9
APS-2-79, a KSR-dependent MEK antagonist, disrupts ATP (biotin) binding within the KSR2-MEK1 complex, achieving an inhibitory concentration (IC50) of 120 nM. This action stabilizes the KSR inactive state and antagonizes oncogenic Ras-MAPK signaling.
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25 mgInquiry1-2 weeks
50 mgInquiry1-2 weeks
100 mgInquiry1-2 weeks
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Product Introduction

Bioactivity
Description
APS-2-79, a KSR-dependent MEK antagonist, disrupts ATP (biotin) binding within the KSR2-MEK1 complex, achieving an inhibitory concentration (IC50) of 120 nM. This action stabilizes the KSR inactive state and antagonizes oncogenic Ras-MAPK signaling.
Chemical Properties
Molecular Weight387.43
FormulaC23H21N3O3
Cas No.2002381-25-9
Storage & Solubility Information
StorageShipping with blue ice.

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Keywords

APS-2-79LY-3325656LY 3325656
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