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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $293 | 6-8 weeks | |
5 mg | $736 | 6-8 weeks | |
10 mg | $987 | 6-8 weeks | |
25 mg | $1,490 | 6-8 weeks | |
50 mg | $1,980 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | RPH-2823, a basic amphotericin analog, is diuretic, natriuretic, and potassium-preserving, inducing a dose-dependent decrease in SCC and an increase in trans-epithelial resistance. |
In vitro | Interacting with the Na+ channel or a regulator site within the apical membrane, RPH-2823 influences transepithelial Na+ transport[2]. |
In vivo | Avoiding the kaliuresis of 25 mumol/kg furosemide in male Wistar rats, RPH 2823 (2.5 mumol/kg) demonstrates its efficacy. RPH 2823 (1 mg/kg and 5 mg/kg, i.v.) exhibits a terminal elimination half-life of 3 h, with approximately 47% of the administered dose being excreted unchanged in the urine[1]. |
Molecular Weight | 370.41 |
Formula | C17H22N8O2 |
Cas No. | 96558-24-6 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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