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HO-PEG5-CH2COOH is a PEG-based linker for PROTACs, joining two essential ligands critical for PROTAC molecule formation, enabling selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | HO-PEG5-CH2COOH is a PEG-based linker for PROTACs, joining two essential ligands critical for PROTAC molecule formation, enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, which consist of two ligands connected by a linker—one targeting an E3 ubiquitin ligase and the other the target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Alias | HO-PEG5-CH2COOH |
Molecular Weight | 296.31 |
Formula | C12H24O8 |
Cas No. | 52026-48-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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