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FLT3 Protein, Human, Recombinant (His & Avi), Biotinylated

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FLT3 Protein, Human, Recombinant (His & Avi), Biotinylated

Catalog No. TMPK-00416

FLT3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in CHO mammalian cells with C-His-Avi tag. The predicted molecular weight is 61.20 kDa and the accession number is P36888-1.

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Pack Size	Price	Availability
100 μg	$814	7-10 days
500 μg	$3,250	7-10 days
1 mg	$5,440	7-10 days

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Biological Description

Biological Information	Immobilized Human FLT3 Ligand, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human FLT3, His Tag with the EC50 of 0.26μg/ml determined by ELISA.
Description	FLT3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in CHO mammalian cells with C-His-Avi tag. The predicted molecular weight is 61.20 kDa and the accession number is P36888-1.
Species	Human
Expression System	CHO Cells
Tag	C-His-Avi
Accession Number	P36888-1
Synonyms	STK-1,FLK2,CD135,FLT-3
Construction	Asn27-Asn541
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	61.20 kDa (predicted). Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the receptor for SCF and FMS, the receptor for M-CSF. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1.