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GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated

GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated
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GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated

Catalog No. TMPK-00196
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 15.19 kDa and the accession number is Q99988-1.
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Pack SizePriceAvailabilityQuantity
100 μg$1,1607-10 days
500 μg$4,6507-10 days
1 mg$7,7607-10 days
Bulk & Custom
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Biological Description

Biological Information
Immobilized Human GFRAL, hFc Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Human GDF15, His Tag with the EC50 of 24ng/ml determined by ELISA.
Description
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 15.19 kDa and the accession number is Q99988-1.
Species
Human
Expression System
E. coli
TagN-His-Avi
Accession NumberQ99988-1
Synonyms
NAG-1,Placental TGF-beta,PTGFBPTGF-β,PDF,Placental TGF-β,PTGF-β,PTGF-beta,MIC1,PTGFB,GDF-15,MIC-1,PTGFBPTGF-beta,GDF15,PLAB,RG-1
Construction
Ala197-Ile308
Protein Purity
> 95% as determined by Tris-Bis PAGE
Molecular Weight15.19 kDa (predicted) same as Tris-Bis PAGE result.
Endotoxin< 1 EU/μg by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM HAc (pH 2.9). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution
Reconstitute the lyophilized protein in 50mM HAc (pH 2.9). The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice.
Research Background
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15.

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.

Keywords