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Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μg | $177 | In Stock | |
100 μg | $498 | 7-10 days | |
200 μg | $851 | 7-10 days | |
500 μg | $2,690 | 7-10 days |
Biological Information | Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 2-12 ng/mL. ![]() |
Description | IL-13 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 12.35 kDa and the accession number is P20109. |
Species | Mouse |
Expression System | HEK293 Cells |
Tag | Tag Free |
Accession Number | P20109 |
Synonyms | Il-13,interleukin 13 |
Construction | The Mouse IL13 (P20109) (Met1-Phe131) was expressed and purified. |
Protein Purity | > 90 % as determined by SDS-PAGE ![]() |
Molecular Weight | 12.35 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.5. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | In general, Lyophilized powders are shipping with blue ice. |
Research Background | Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses, and diseases. Also, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody are more importantly implicated as a central mediator of immunoregulatory processes in various cell types.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
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