Loaded HHLA2 Protein, Human, Recombinant (His) (Cat#TMPY-05016) on His1K Biosensor, can bind KIR3DL3 Protein, Human, Recombinant (hFc) (Cat#TMPY-07135) with an affinity constant of 18.5 nM as determined in BLI assay (Sartorius Octet RED384) (QC tested).

KIR3DL3 Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q8N743.

Human

HEK293 Cells

KIRC1,KIR44,KIR3DL7,KIR2DL5B,CD158Z

A DNA sequence encoding the Human KIR3DL3 (NP_703144.2) (Met1-Leu322) was expressed with the Fc region of human IgG1 at the C-terminus.

≥ 95% as determined by SDS-PAGE. ≥ 90% as determined by SEC-HPLC.

Please refer to the lot-specific COA.

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

KIR3DL3 (Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Long Cytoplasmic Tail 3) is a Protein Coding gene. KIR3DL3 is a framework gene of the Leukocyte Receptor Complex, present in all individuals and haplotypes analyzed to date.KIR3DL3 alleles were characterized by two families and one unrelated individual. The most centromeric gene in the human KIR cluster is KIR3DL3. The encoded protein belongs to the immunoglobulin superfamily. KIR3DL3 has only one immunoreceptor tyrosine-based inhibitory motif and lacks the exon encoding the stem between the Immunoglobulin domains and the transmembrane region. KIR3DL3 gene is not a pseudogene but encodes a protein that is not expressed in healthy individuals. Protein expression might be induced under certain developmental or pathological situations.