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PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated

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PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated

Catalog No. TMPK-00662

B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26 kDa and the accession number is G7PSE7.

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Pack Size	Price	Availability
100 μg	$814	7-10 days
500 μg	$3,250	7-10 days
1 mg	$5,440	7-10 days

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Biological Description

Biological Information	Immobilized Biotinylated Cynomolgus/Rhesus macaque PD-L1, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-PD-L1 Antibody, hFc Tag with the EC50 of 4.0ng/ml determined by ELISA.
Description	B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26 kDa and the accession number is G7PSE7.
Species	Cynomolgus,Rhesus
Expression System	HEK293 Cells
Tag	C-His
Accession Number	G7PSE7
Synonyms	PDCD1LG1,B7-H1,B7H1,CD274,B7-H,PDCD1L1,PD-L1B7 homolog 1,PDL1,PD-L1
Construction	Phe19-Arg238
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	26 kDa (predicted). Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance.

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Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

PDL-1 CD 274 PDL 1 CD-274