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(±)13(14)-EpDPA

Catalog No. T35496Cas No. 895127-64-7

Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)13(14)-EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 13,14-double bond of DHA. It has been detected in rat brain and spinal cord and is a preferred substrate for soluble epoxide hydrolase with a Km value of 3.2 μM. (±)13(14)-EpDPA demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models. (±)13(14)-EpDPA and other epoxy metabolites of DHA are also reported to potently inhibit angiogenesis and tumor growth in in vitro assays.

(±)13(14)-EpDPA
Other Forms of (±)13(14)-EpDPA:
(±)10(11)-EpDPAT35493895127-65-8
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(±)19(20)-EpDPAT37238
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19R(20S)-EpDPAT362182242542-60-3
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(±)7(8)-EpDPAT35497895127-66-9
View details
(±)16(17)-EpDPAT37235155073-46-4
View details

(±)13(14)-EpDPA

Catalog No. T35496Cas No. 895127-64-7
Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)13(14)-EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 13,14-double bond of DHA. It has been detected in rat brain and spinal cord and is a preferred substrate for soluble epoxide hydrolase with a Km value of 3.2 μM. (±)13(14)-EpDPA demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models. (±)13(14)-EpDPA and other epoxy metabolites of DHA are also reported to potently inhibit angiogenesis and tumor growth in in vitro assays.
Pack SizePriceAvailabilityQuantity
25 μg$9835 days
50 μg$19535 days
100 μg$36335 days
500 μg$1,60035 days
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Product Introduction

Bioactivity
Description
Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)13(14)-EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 13,14-double bond of DHA. It has been detected in rat brain and spinal cord and is a preferred substrate for soluble epoxide hydrolase with a Km value of 3.2 μM. (±)13(14)-EpDPA demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models. (±)13(14)-EpDPA and other epoxy metabolites of DHA are also reported to potently inhibit angiogenesis and tumor growth in in vitro assays.
Chemical Properties
Molecular Weight344.495
FormulaC22H32O3
Cas No.895127-64-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 20 mg/mL
Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL
DMF: 25 mg/mL
Ethanol: 50 mg/mL

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Keywords

13(14)-EpDPA(±)13(14)EpDPA(±)13(14) EpDPA
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