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(R)-GSK-3685032

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Catalog No. T39648Cas No. 2170140-50-6

(R)-GSK-3685032 is the R-enantiomer of GSK-3685032, a first-in-class, non-time-dependent, non-covalent, reversible, selective DNMT1 inhibitor with an IC50 of 0.036 μM, which induces robust loss of DNA methylation, transcriptional activation, and inhibition of cancer cell growth.

(R)-GSK-3685032
Other Forms of (R)-GSK-3685032:
GSK3685032T95732170137-61-6
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(R)-GSK-3685032

😃Good
Catalog No. T39648Cas No. 2170140-50-6
(R)-GSK-3685032 is the R-enantiomer of GSK-3685032, a first-in-class, non-time-dependent, non-covalent, reversible, selective DNMT1 inhibitor with an IC50 of 0.036 μM, which induces robust loss of DNA methylation, transcriptional activation, and inhibition of cancer cell growth.
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2 mg$1,2085 days
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Product Introduction

Bioactivity
Description
(R)-GSK-3685032 is the R-enantiomer of GSK-3685032, a first-in-class, non-time-dependent, non-covalent, reversible, selective DNMT1 inhibitor with an IC50 of 0.036 μM, which induces robust loss of DNA methylation, transcriptional activation, and inhibition of cancer cell growth.
Chemical Properties
Molecular Weight420.54
FormulaC22H24N6OS
Cas No.2170140-50-6
Relative Density.1.33 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

GSK 3685032GSK-3685032GSK3685032(R)GSK3685032(R) GSK 3685032
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