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(R)-Omeprazole (sodium salt)

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Catalog No. T36840Cas No. 161796-77-6

(R)-Omeprazole is the inactive isomer of omeprazole , a gastric proton-pump inhibitor. A stereoselective hydroxylation of (R)-omeprazole is mediated primarily by cytochrome P450 (CYP) 2C19, whereas CYP3A4 favors sulfoxidation of the active (S)-enantiomer . (R)-Omeprazole has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 8.1 μM).

(R)-Omeprazole (sodium salt)
Other Forms of (R)-Omeprazole (sodium salt):

(R)-Omeprazole (sodium salt)

😃Good
Catalog No. T36840Cas No. 161796-77-6
(R)-Omeprazole is the inactive isomer of omeprazole , a gastric proton-pump inhibitor. A stereoselective hydroxylation of (R)-omeprazole is mediated primarily by cytochrome P450 (CYP) 2C19, whereas CYP3A4 favors sulfoxidation of the active (S)-enantiomer . (R)-Omeprazole has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 8.1 μM).
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500 μg188 €35 days
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5 mg1.434 €35 days
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Product Introduction

Bioactivity
Description
(R)-Omeprazole is the inactive isomer of omeprazole , a gastric proton-pump inhibitor. A stereoselective hydroxylation of (R)-omeprazole is mediated primarily by cytochrome P450 (CYP) 2C19, whereas CYP3A4 favors sulfoxidation of the active (S)-enantiomer . (R)-Omeprazole has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 8.1 μM).
Chemical Properties
Molecular Weight368.41
FormulaC17H19N3NaO3S
Cas No.161796-77-6
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 1 mg/mL
DMSO: 5 mg/mL
PBS (pH 7.2): 5 mg/mL
DMF: 5 mg/mL

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Keywords

(R) Omeprazole (sodium salt)(R)Omeprazole (sodium salt)Omeprazole
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