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Omeprazole Sodium

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Purity:99.57%

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COA HNMR HPLC

Omeprazole Sodium

Catalog No. T22391Cas No. 95510-70-6

Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Omeprazole Sodium shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole Sodium inhibits growth of Gram-positive and Gram-negative bacteria.

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Pack Size	Price	Availability
100 mg	$41	In Stock
200 mg	$58	In Stock
500 mg	$97	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock

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Product Introduction

Bioactivity

Description	Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Omeprazole Sodium shows competitive inhibition of CYP2C19 activity with a Ki of 2 to 6 μM. Omeprazole Sodium inhibits growth of Gram-positive and Gram-negative bacteria.
Targets&IC50	CYP2C19:2 to 6 μM(Ki)
In vivo	Omeprazole Sodium virtually eliminated intragastric acidity in all patients: the median 24 hour intragastric pH rose from 1.4 to 5.3 and the mean hourly hydrogen ion activity fell from 38.50 to 1.95 mmol(mEq)/1 (p less than 0.001)[1]

Chemical Properties

Molecular Weight	367.4
Formula	C17H18N3NaO3S
Cas No.	95510-70-6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 120 mg/mL (326.62 mM), Sonication is recommended.

H2O: 5.5 mg/mL (14.97 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7218 mL	13.6091 mL	27.2183 mL	136.0915 mL
5 mM	0.5444 mL	2.7218 mL	5.4437 mL	27.2183 mL
10 mM	0.2722 mL	1.3609 mL	2.7218 mL	13.6091 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.1361 mL	0.6805 mL	1.3609 mL	6.8046 mL
50 mM	0.0544 mL	0.2722 mL	0.5444 mL	2.7218 mL
100 mM	0.0272 mL	0.1361 mL	0.2722 mL	1.3609 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc