Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(Rac)-Nebivolol ((Rac)-R 065824) is a racemic isomer of Nebivolol. Nebivolol is a selective antagonist of β1-adrenergic receptor (IC 50= 0.8 nM). Nebivolol shows Vasodilatory activity. In the early stages of ethanol-induced cardiac toxicity, Nebivolol can prevent up-regulation of Nox2/NADPH oxidase and lipoperoxidation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 1,520.00 | |
50 mg | 10-14 weeks | $ 1,980.00 | |
100 mg | 10-14 weeks | $ 2,500.00 |
Description | (Rac)-Nebivolol ((Rac)-R 065824) is a racemic isomer of Nebivolol. Nebivolol is a selective antagonist of β1-adrenergic receptor (IC 50= 0.8 nM). Nebivolol shows Vasodilatory activity. In the early stages of ethanol-induced cardiac toxicity, Nebivolol can prevent up-regulation of Nox2/NADPH oxidase and lipoperoxidation. |
In vivo | Nebivolol (10 mg/kg; daily for 7 days) significantly enhances endothelial function and elevates P-VASP levels while preventing NOS III uncoupling and markedly inhibiting NADPH oxidase in Angiotensin II-treated rats [3]. |
Molecular Weight | 405.43 |
Formula | C22H25F2NO4 |
CAS No. | 99200-09-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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(Rac)-Nebivolol 99200-09-6 inhibitor inhibit