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(S)-JDQ-443

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Catalog No. T72971Cas No. 2653994-10-4
Alias (S)-NVP-JDQ443

(S)-JDQ-443 is an isomer of JDQ-443, which is an orally active, potent, selective, and covalent KRAS G12C inhibitor, showing antitumor activity [1] [2].

(S)-JDQ-443
Other Forms of (S)-JDQ-443:
OpnurasibT402922653994-08-0
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(S)-JDQ-443

😃Good
Catalog No. T72971Alias (S)-NVP-JDQ443Cas No. 2653994-10-4
(S)-JDQ-443 is an isomer of JDQ-443, which is an orally active, potent, selective, and covalent KRAS G12C inhibitor, showing antitumor activity [1] [2].
Pack SizePriceAvailabilityQuantity
25 mg$1,42010-14 weeks
50 mg$1,85010-14 weeks
100 mg$2,81010-14 weeks
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Product Introduction

Bioactivity
Description
(S)-JDQ-443 is an isomer of JDQ-443, which is an orally active, potent, selective, and covalent KRAS G12C inhibitor, showing antitumor activity [1] [2].
Alias(S)-NVP-JDQ443
Chemical Properties
Molecular Weight526.03
FormulaC29H28ClN7O
Cas No.2653994-10-4
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

NVP-JDQ-443NVP-JDQ443JDQ 443JDQ-443NVP-JDQ 443JDQ443
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