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(S,R,S)-AHPC-C4-NH2

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Catalog No. T18666Cas No. 2138439-53-7
Alias VH032-C4-NH2

(S,R,S)-AHPC-C4-NH2 is a custom-synthesized conjugate consisting of an E3 ligase ligand-linker, combining a VHL ligand based on (S,R,S)-AHPC with a linker specifically designed for EED-targeted PROTAC[1].

(S,R,S)-AHPC-C4-NH2
Other Forms of (S,R,S)-AHPC-C4-NH2:

(S,R,S)-AHPC-C4-NH2

😃Good
Catalog No. T18666Alias VH032-C4-NH2Cas No. 2138439-53-7
(S,R,S)-AHPC-C4-NH2 is a custom-synthesized conjugate consisting of an E3 ligase ligand-linker, combining a VHL ligand based on (S,R,S)-AHPC with a linker specifically designed for EED-targeted PROTAC[1].
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Product Introduction

Bioactivity
Description
(S,R,S)-AHPC-C4-NH2 is a custom-synthesized conjugate consisting of an E3 ligase ligand-linker, combining a VHL ligand based on (S,R,S)-AHPC with a linker specifically designed for EED-targeted PROTAC[1].
In vitro
PROTACs are composed of two distinct ligands linked together: one binds to an E3 ubiquitin ligase, and the other targets a specific protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs selectively degrade these target proteins.
AliasVH032-C4-NH2
Chemical Properties
Molecular Weight529.7
FormulaC27H39N5O4S
Cas No.2138439-53-7
Relative Density.1.227 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

(S,R,S)-AHPC-C-4-NH2AHPC-C4-NH2(S,R,S)AHPCC4NH2(S,R,S) AHPC C4 NH2
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