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(S,R,S)-AHPC-C8-NH2

Catalog No. T39873Cas No. 2341796-79-8
Alias VH032-C8-NH2, (S,R,S)-AHPC-C8-NH2

(S, R, S)-AHPC-C8-NH2 (VH032-C8-NH2) is an E3 ligase ligand-linker conjugate. This compound comprises the VH032-based VHL ligand and a linker, specifically designed for AKT PROTAC degrader applications.

(S,R,S)-AHPC-C8-NH2

(S,R,S)-AHPC-C8-NH2

Catalog No. T39873Alias VH032-C8-NH2, (S,R,S)-AHPC-C8-NH2Cas No. 2341796-79-8
(S, R, S)-AHPC-C8-NH2 (VH032-C8-NH2) is an E3 ligase ligand-linker conjugate. This compound comprises the VH032-based VHL ligand and a linker, specifically designed for AKT PROTAC degrader applications.
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Product Introduction

Bioactivity
Description
(S, R, S)-AHPC-C8-NH2 (VH032-C8-NH2) is an E3 ligase ligand-linker conjugate. This compound comprises the VH032-based VHL ligand and a linker, specifically designed for AKT PROTAC degrader applications.
In vitro
PROTACs, or proteolysis-targeting chimeras, are composed of two distinct ligands joined by a linker. One of these ligands binds to a specific protein target, while the other binds to an E3 ubiquitin ligase. When the PROTAC binds to both the target protein and the E3 ligase, it triggers the ubiquitin-proteasome system within cells to degrade the target protein, thereby providing a mechanism for targeted protein degradation.
AliasVH032-C8-NH2, (S,R,S)-AHPC-C8-NH2
Chemical Properties
Molecular Weight585.81
FormulaC31H47N5O4S
Cas No.2341796-79-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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