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(S,R,S)-AHPC-C8-NH2 hydrochloride

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Catalog No. T39931Cas No. 2376139-49-8
Alias VH032-C8-NH2 hydrochloride, (S,R,S)-AHPC-C8-NH2 hydrochloride

'(S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) hydrochloride is a synthetic E3 ligase ligand-linker conjugate, consisting of the VH032-based VHL ligand and a linker for use in PROTAC technology.'

(S,R,S)-AHPC-C8-NH2 hydrochloride
Other Forms of (S,R,S)-AHPC-C8-NH2 hydrochloride:

(S,R,S)-AHPC-C8-NH2 hydrochloride

😃Good
Catalog No. T39931Alias VH032-C8-NH2 hydrochloride, (S,R,S)-AHPC-C8-NH2 hydrochlorideCas No. 2376139-49-8
'(S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) hydrochloride is a synthetic E3 ligase ligand-linker conjugate, consisting of the VH032-based VHL ligand and a linker for use in PROTAC technology.'
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Product Introduction

Bioactivity
Description
'(S,R,S)-AHPC-C8-NH2 (VH032-C8-NH2) hydrochloride is a synthetic E3 ligase ligand-linker conjugate, consisting of the VH032-based VHL ligand and a linker for use in PROTAC technology.'
In vitro
PROTACs consist of two distinct ligands linked together: one binds to an E3 ubiquitin ligase, and the other to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
AliasVH032-C8-NH2 hydrochloride, (S,R,S)-AHPC-C8-NH2 hydrochloride
Chemical Properties
Molecular Weight622.27
FormulaC31H48ClN5O4S
Cas No.2376139-49-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

(S,R,S)AHPCC8NH2 hydrochloride(S,R,S) AHPC C8 NH2 hydrochloride(S,R,S)-AHPC-C-8-NH2 hydrochlorideVH032-C8-NH2 HydrochlorideAHPC-C8-NH2 Hydrochloride
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