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[D-Trp34]-Neuropeptide Y Acetate

[D-Trp34]-Neuropeptide Y Acetate
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Purity:99.73%
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[D-Trp34]-Neuropeptide Y Acetate

Catalog No. TP1984L
[D-Trp34]-Neuropeptide Y Acetate is a potent and selective agonist of neuropeptide Y (NPY) Y5 receptor. [D-Trp34]-Neuropeptide acetate Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y Acetate markedly increases food intake in rats.
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Pack SizePriceAvailabilityQuantity
1 mg$195In Stock
5 mg$450In Stock
10 mg$675In Stock
25 mg$1,154In Stock
50 mg$1,730In Stock
100 mg$2,595In Stock
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Product Introduction

Bioactivity
Description
[D-Trp34]-Neuropeptide Y Acetate is a potent and selective agonist of neuropeptide Y (NPY) Y5 receptor. [D-Trp34]-Neuropeptide acetate Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y Acetate markedly increases food intake in rats.
In vitro
[D-Trp34]-Neuropeptide Y Acetate exhibits pKi values of 6.49, 5.43, 7.08, 7.53, 6.55, 5.95, 6.85, 7.41 for hY1, hY2, hY4, hY5, rY1, rY2, rY4, rY5 in CHO cells. [D-Trp34]-Neuropeptide Y Acetate exhibits pEC50 values of 6.44, <6, 6.28,7.82 for rY1, rY2 in CHO cells and rY4, rY5 in HEK-293 cells[1].
In vivo
[D-Trp34]-Neuropeptide Y Acetate (0, 8 and 16 μg/rat; I.C.V) stimulats food intake to the same extent in both lean and obese rats 1 h after injection at a dose of 16 μg in male Zucker rats[2].
Alias[D-Trp34]-Neuropeptide Y Acetate (153549-84-9 Free base)
Chemical Properties
Molecular Weight4371.78
FormulaC198H293N55O58
Cas No.
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year

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