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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | Backorder |
Description | β-Secretase Inhibitor II is a tripeptide aldehyde compound that acts as an inhibitor of β-Secretase. It exhibits a simple structure and has an inhibitory potency of IC50 = 700 nM against total Aβ and IC50 = 2.5 μM specifically against Aβ 1-42. This compound is particularly useful in research related to Alzheimer's disease. |
Targets&IC50 | β-Amyloid:700 nM (IC50), β-Amyloid (1–42):2.5 μM (IC50) |
In vitro | β-Secretase Inhibitor II, a simple tripeptide aldehyde, exhibits inhibitory activity on the formation of both total amyloid beta (Aβ) and Aβ 1–42, with IC50 values of 700 nM and 2.5 μM, respectively. This compound demonstrates dose-dependent inhibition[1]. |
Molecular Weight | 461.603 |
Formula | C25H39N3O5 |
Cas No. | 263563-09-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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