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1-(7-carbamimidamidoheptyl)guanidine 2HCl

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Purity:95.00%

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COA HNMR

1-(7-carbamimidamidoheptyl)guanidine 2HCl

Catalog No. T50092Cas No. 2193061-39-9

1,1'-(Heptane-1,7-diyl)diguanidine dihydrochloride is a potent and selective small molecule inhibitor of glycogen synthase kinase-3 (GSK-3). It is used in studies of stem cell differentiation, tumors and neurodegenerative diseases.

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Pack Size	Price	Availability
1 mg	$143	In Stock
2 mg	$215	In Stock
5 mg	$331	In Stock
10 mg	$496	In Stock
25 mg	$792	In Stock
50 mg	$1,120	In Stock
100 mg	$1,520	In Stock
500 mg	$2,970	In Stock
1 mL x 10 mM (in DMSO)	$317	In Stock

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Product Introduction

Bioactivity

Description	1,1'-(Heptane-1,7-diyl)diguanidine dihydrochloride is a potent and selective small molecule inhibitor of glycogen synthase kinase-3 (GSK-3). It is used in studies of stem cell differentiation, tumors and neurodegenerative diseases.
Alias	1-(7-carbamimidamidoheptyl)guanidine dihydrochloride, 1,1'-(Heptane-1,7-diyl)diguanidine 2HCl

Chemical Properties

Molecular Weight	287.23
Formula	C9H24Cl2N6
Cas No.	2193061-39-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (174.08 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4815 mL	17.4077 mL	34.8153 mL	174.0765 mL
5 mM	0.6963 mL	3.4815 mL	6.9631 mL	34.8153 mL
10 mM	0.3482 mL	1.7408 mL	3.4815 mL	17.4077 mL
20 mM	0.1741 mL	0.8704 mL	1.7408 mL	8.7038 mL
50 mM	0.0696 mL	0.3482 mL	0.6963 mL	3.4815 mL
100 mM	0.0348 mL	0.1741 mL	0.3482 mL	1.7408 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc