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1-(2,4-difluorophenyl)guanidine hydrochloride

Catalog No. T50030Cas No. 112677-40-4

1-(2,4-difluorophenyl)guanidine hydrochloride is a compound that is a potent and selective inhibitor of the voltage-gated sodium channel Nav1.7, a key player in pain signaling. It is therefore able to reduce pain signaling, resulting in an analgesic effect.

1-(2,4-difluorophenyl)guanidine hydrochloride

1-(2,4-difluorophenyl)guanidine hydrochloride

Purity: 95.00%
Catalog No. T50030Cas No. 112677-40-4
1-(2,4-difluorophenyl)guanidine hydrochloride is a compound that is a potent and selective inhibitor of the voltage-gated sodium channel Nav1.7, a key player in pain signaling. It is therefore able to reduce pain signaling, resulting in an analgesic effect.
Pack SizePriceAvailabilityQuantity
5 mg$40In Stock
10 mg$58In Stock
25 mg$103In Stock
50 mg$153In Stock
100 mg$232In Stock
200 mg$347In Stock
1 mL x 10 mM (in DMSO)$41In Stock
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Purity:95.00%
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Product Introduction

Bioactivity
Description
1-(2,4-difluorophenyl)guanidine hydrochloride is a compound that is a potent and selective inhibitor of the voltage-gated sodium channel Nav1.7, a key player in pain signaling. It is therefore able to reduce pain signaling, resulting in an analgesic effect.
Chemical Properties
Molecular Weight207.61
FormulaC7H8ClF2N3
Cas No.112677-40-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (216.75 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.8167 mL24.0836 mL48.1672 mL240.8362 mL
5 mM0.9633 mL4.8167 mL9.6334 mL48.1672 mL
10 mM0.4817 mL2.4084 mL4.8167 mL24.0836 mL
20 mM0.2408 mL1.2042 mL2.4084 mL12.0418 mL
50 mM0.0963 mL0.4817 mL0.9633 mL4.8167 mL
100 mM0.0482 mL0.2408 mL0.4817 mL2.4084 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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