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1-(3-chloropyridin-2-yl)piperazine 2HCl

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Catalog No. T50018Cas No. 1193389-39-7

1-(3-chloropyridin-2-yl)piperazine dihydrochloride is a piperazine analog often used as a reagent in organic synthesis, as a ligand in coordination chemistry, and as a drug in pharmaceuticals. It is an inhibitor of DPP4, and DPP4 inhibition has been shown to have beneficial effects in the treatment of certain diseases such as type 2 diabetes and obesity.

1-(3-chloropyridin-2-yl)piperazine 2HCl

1-(3-chloropyridin-2-yl)piperazine 2HCl

🥰Excellent
Purity: 97.20%
Catalog No. T50018Cas No. 1193389-39-7
1-(3-chloropyridin-2-yl)piperazine dihydrochloride is a piperazine analog often used as a reagent in organic synthesis, as a ligand in coordination chemistry, and as a drug in pharmaceuticals. It is an inhibitor of DPP4, and DPP4 inhibition has been shown to have beneficial effects in the treatment of certain diseases such as type 2 diabetes and obesity.
Pack SizePriceAvailabilityQuantity
5 mg$30In Stock
10 mg$45In Stock
25 mg$77In Stock
50 mg$115In Stock
100 mg$172In Stock
200 mg$259In Stock
1 mL x 10 mM (in DMSO)$38In Stock
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Purity:97.20%
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Product Introduction

Bioactivity
Description
1-(3-chloropyridin-2-yl)piperazine dihydrochloride is a piperazine analog often used as a reagent in organic synthesis, as a ligand in coordination chemistry, and as a drug in pharmaceuticals. It is an inhibitor of DPP4, and DPP4 inhibition has been shown to have beneficial effects in the treatment of certain diseases such as type 2 diabetes and obesity.
Chemical Properties
Molecular Weight270.587
FormulaC9H14Cl3N3
Cas No.1193389-39-7
SmilesCl.Cl.Clc1cccnc1N1CCNCC1
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (203.27 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6957 mL18.4783 mL36.9567 mL184.7835 mL
5 mM0.7391 mL3.6957 mL7.3913 mL36.9567 mL
10 mM0.3696 mL1.8478 mL3.6957 mL18.4783 mL
20 mM0.1848 mL0.9239 mL1.8478 mL9.2392 mL
50 mM0.0739 mL0.3696 mL0.7391 mL3.6957 mL
100 mM0.0370 mL0.1848 mL0.3696 mL1.8478 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

1-(3-chloropyridin-2-yl)piperazine1 (3 chloropyridin 2 yl)piperazine dihydrochloride1(3chloropyridin2yl)piperazine dihydrochloride
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