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15(S)-HETrE

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Catalog No. T37400Cas No. 92693-02-2

15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid. It inhibits 5-LO in human PMNL with an IC50 value of 4.6 μM. In RBL cells, 15(S)-HETrE also inhibits 5-LO, but is approximately 1/20 as potent as 15(S)-HpETE.

15(S)-HETrE
Other Forms of 15(S)-HETrE:

15(S)-HETrE

😃Good
Catalog No. T37400Cas No. 92693-02-2
15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid. It inhibits 5-LO in human PMNL with an IC50 value of 4.6 μM. In RBL cells, 15(S)-HETrE also inhibits 5-LO, but is approximately 1/20 as potent as 15(S)-HpETE.
Pack SizePriceAvailabilityQuantity
25 μg$198 35 days
50 μg$375 35 days
100 μg$686 35 days
500 μg$1,550 35 days
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Product Introduction

Bioactivity
Description
15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid. It inhibits 5-LO in human PMNL with an IC50 value of 4.6 μM. In RBL cells, 15(S)-HETrE also inhibits 5-LO, but is approximately 1/20 as potent as 15(S)-HpETE.
Chemical Properties
Molecular Weight322.48
FormulaC20H34O3
Cas No.92693-02-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
0.1 M Na2CO3: 2 mg/mL (6.2 mM), Sonication is recommended.
Ethanol: Miscible
DMF: Miscible
PBS (pH 7.2): 0.8 mg/mL (2.48 mM), Sonication is recommended.
DMSO: Miscible
Solution Preparation Table
PBS (pH 7.2)/0.1 M Na2CO3
1mg5mg10mg50mg
1 mM3.1010 mL15.5048 mL31.0097 mL155.0484 mL
0.1 M Na2CO3
1mg5mg10mg50mg
5 mM0.6202 mL3.1010 mL6.2019 mL31.0097 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

15(S) HETrE15(S)HETrE15HETrE
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