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12(S)-HETrE

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Catalog No. T36773Cas No. 72710-10-2

12(S)-HETrE is produced by 12-lipoxygenase oxidation of dihomo-γ-linolenic acid (DGLA). 12(S)-HETrE is reported to inhibit agonist-mediated platelet activation (IC50 = 40 μM), α granule secretion, integrin αIIbβ3 activation, Rap1 activation, and thrombin-induced clot retraction in vitro.

12(S)-HETrE
Other Forms of 12(S)-HETrE:

12(S)-HETrE

😃Good
Catalog No. T36773Cas No. 72710-10-2
12(S)-HETrE is produced by 12-lipoxygenase oxidation of dihomo-γ-linolenic acid (DGLA). 12(S)-HETrE is reported to inhibit agonist-mediated platelet activation (IC50 = 40 μM), α granule secretion, integrin αIIbβ3 activation, Rap1 activation, and thrombin-induced clot retraction in vitro.
Pack SizePriceAvailabilityQuantity
25 μg$23035 days
50 μg$43835 days
100 μg$82835 days
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Product Introduction

Bioactivity
Description
12(S)-HETrE is produced by 12-lipoxygenase oxidation of dihomo-γ-linolenic acid (DGLA). 12(S)-HETrE is reported to inhibit agonist-mediated platelet activation (IC50 = 40 μM), α granule secretion, integrin αIIbβ3 activation, Rap1 activation, and thrombin-induced clot retraction in vitro.
Chemical Properties
Molecular Weight322.489
FormulaC20H34O3
Cas No.72710-10-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMF: Miscible
DMSO: Miscible
0.1 M Na2CO3: 2 mg/mL
PBS (pH 7.2): 0.8 mg/mL
Ethanol: Miscible

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

12HETrE12(S)HETrE12(S) HETrE
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