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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $893 | Backorder |
Description | 18-Oxocortisol is a cortisol derivative generated by aldosterone synthase (CYP11B2). It acts as a naturally occurring mineralocorticoid agonist and serves as a biomarker in adrenal vein sampling. |
In vivo | Administration of 18-oxocortisol in rats triggers mineralocorticoid-type hypertension, characterized by hypokalemia, as well as enlargement of cardiac and renal tissues and cardiovascular lesions. Similarly, when administered to sheep, 18-oxocortisol leads to a swift elevation in blood pressure. Nonetheless, achieving an increase in blood pressure necessitates high doses[3]. |
Molecular Weight | 376.449 |
Formula | C21H28O6 |
Cas No. | 2410-60-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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