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2-Di-1-ASP

🥰Excellent
Catalog No. T18883Cas No. 2156-29-8

2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. It has selective for G-quadruplex (G4) and double-stranded DNA.

2-Di-1-ASP

2-Di-1-ASP

🥰Excellent
Purity: 99.98%
Catalog No. T18883Cas No. 2156-29-8
2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. It has selective for G-quadruplex (G4) and double-stranded DNA.
Pack SizePriceAvailabilityQuantity
50 mg$29In Stock
1 mL x 10 mM (in DMSO)$30In Stock
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Purity:99.98%
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COA HNMR HPLC
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Product Introduction

Bioactivity
Description
2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. It has selective for G-quadruplex (G4) and double-stranded DNA.
In vitro
Compound 18a (2-Di-1-ASP) exhibits marked fluorescence intensification, achieving up to a 300-fold increase, specifically in the presence of G4 structures, while maintaining significant selectivity against double-stranded DNA. Moreover, 2-Di-1-ASP demonstrates fluorimetric selectivity for parallel forms of G4-DNA, including c-kit2, c-myc, and c-kit87up.
Chemical Properties
Molecular Weight366.24
FormulaC16H19IN2
Cas No.2156-29-8
Smiles[I-].CN(C)c1ccc(\C=C\c2cccc[n+]2C)cc1
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 20 mg/mL (54.61 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7304 mL13.6522 mL27.3045 mL136.5225 mL
5 mM0.5461 mL2.7304 mL5.4609 mL27.3045 mL
10 mM0.2730 mL1.3652 mL2.7304 mL13.6522 mL
20 mM0.1365 mL0.6826 mL1.3652 mL6.8261 mL
50 mM0.0546 mL0.2730 mL0.5461 mL2.7304 mL

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Keywords

probesmono-stryrylmitochondrialInhibitorinhibitG-quadruplexG4-DNAFluorescentdye2-Di-1-ASP2Di1ASP2 Di 1 ASP
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