Shopping Cart
- Remove All
Your shopping cart is currently empty
21-deacetyldeflazacort
🥰Excellent
Catalog No. T29328Cas No. 13649-57-5
21-deacetyldeflazacort is a metabolite of Deflazacort, which is a systemic corticosteroid and a derivative of prednisolone.
21-deacetyldeflazacort
🥰Excellent
Purity: 99.29%
Catalog No. T29328Cas No. 13649-57-5
21-deacetyldeflazacort is a metabolite of Deflazacort, which is a systemic corticosteroid and a derivative of prednisolone.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $30 | In Stock | |
| 5 mg | $74 | In Stock | |
| 10 mg | $118 | In Stock | |
| 25 mg | $225 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $81 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreSelect Batch
Purity:99.29%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | 21-Desacetyl Deflazacort is a metabolite of Deflazacort (sc-204709), which is a systemic corticosteroid and a derivative of prednisolone. It is used for lupus and rheumatoid arthritis. |
| In vitro | 21-deacetyldeflazacort displaces [3H]dexamethasone from its cytosol receptor sites in rat kidney, thymus and liver in vitro. |
| In vivo | 21-deacetyldeflazacort inhibited 48-h homologous passive cutaneous anaphylaxis in rats, but had no significant effects on active systemic anaphylaxis in mice, on the Schultz-Dale reaction in the isolated guinea-pig trachea or on compound 48/80-induced histamine release in rat peritoneal mast cells. 21-deacetyldeflazacort inhibited reversed cutaneous anaphylaxis in rats and the Arthus reaction in mice[1]. |
| Molecular Weight | 399.48 |
| Formula | C23H29NO5 |
| Cas No. | 13649-57-5 |
| Smiles | C(CO)(=O)[C@]12[C@]3(C)[C@@](C[C@]1(OC(C)=N2)[H])([C@]4([C@]([C@@H](O)C3)([C@]5(C)C(CC4)=CC(=O)C=C5)[H])[H])[H] |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 65 mg/ml (162.71 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy 21-deacetyldeflazacort | purchase 21-deacetyldeflazacort | 21-deacetyldeflazacort cost | order 21-deacetyldeflazacort | 21-deacetyldeflazacort chemical structure | 21-deacetyldeflazacort in vivo | 21-deacetyldeflazacort in vitro | 21-deacetyldeflazacort formula | 21-deacetyldeflazacort molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.