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4,4'-DIMETHOXYBENZIL

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Catalog No. T5943Cas No. 1226-42-2
Alias p-Anisil

4,4'-Dimethoxybenzil (p-Anisil) is a human intestinal carboxyl esterase (hiCE) inhibitor( Ki : 70 nM).

4,4'-DIMETHOXYBENZIL

4,4'-DIMETHOXYBENZIL

🥰Excellent
Purity: 99.04%
Catalog No. T5943Alias p-AnisilCas No. 1226-42-2
4,4'-Dimethoxybenzil (p-Anisil) is a human intestinal carboxyl esterase (hiCE) inhibitor( Ki : 70 nM).
Pack SizePriceAvailabilityQuantity
1 g$29In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:99.04%
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Product Introduction

Bioactivity
Description
4,4'-Dimethoxybenzil (p-Anisil) is a human intestinal carboxyl esterase (hiCE) inhibitor( Ki : 70 nM).
Targets&IC50
Carboxyl esterase (human intestine):70 nM(Ki)
In vitro
HiCE inhibitors (4,4'-Dimethoxybenzil) mitigate irinotecan-induced diarrhea, thereby enhancing the anticancer efficacy of irinotecan.
Aliasp-Anisil
Chemical Properties
Molecular Weight270.28
FormulaC16H14O4
Cas No.1226-42-2
SmilesC(C(=O)C1=CC=C(OC)C=C1)(=O)C2=CC=C(OC)C=C2
Relative Density.1.2117 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 6.25 mg/mL (23.12 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6999 mL18.4993 mL36.9987 mL184.9933 mL
5 mM0.7400 mL3.6999 mL7.3997 mL36.9987 mL
10 mM0.3700 mL1.8499 mL3.6999 mL18.4993 mL
20 mM0.1850 mL0.9250 mL1.8499 mL9.2497 mL

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Keywords

Inhibitorinhibithuman intestinal carboxyl esterase (hiCE)4,4'-DIMETHOXYBENZIL4,4'-Dimethoxybenzil4,4'DIMETHOXYBENZIL4,4' DIMETHOXYBENZIL
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