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4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol

Name: 4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol
Brand: TargetMol
SKU: T17333
Rating: 4.5 (1 reviews)

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Catalog No. T17333Cas No. 58884-35-8

4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol is an alkyl chain-derived PROTAC linker used in the synthesis of PROTACs[1].

4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol

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Catalog No. T17333Cas No. 58884-35-8

4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol is an alkyl chain-derived PROTAC linker used in the synthesis of PROTACs[1].

Pack Size	Price	Availability	Quantity
100 mg	Inquiry	7-10 days
500 mg	Inquiry	7-10 days

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Product Introduction

Bioactivity

Description	4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol is an alkyl chain-derived PROTAC linker used in the synthesis of PROTACs[1].
In vitro	PROTACs consist of two ligands connected by a linker: one targets an E3 ubiquitin ligase, and the other targets the protein of interest. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Chemical Properties

Molecular Weight	188.19
Formula	C₉H₈N₄O
Cas No.	58884-35-8
Relative Density.	1.322 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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Keywords

Alkyl-Chain4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol4(6Methyl1,2,4,5tetrazin3yl)phenol4 (6 Methyl 1,2,4,5 tetrazin 3 yl)phenol

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