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HM-cytosine

🥰Excellent
Catalog No. T35363Cas No. 1123-95-1
Alias 5-Hydroxymethylcytosine, 5hmC

HM-cytosine (5hmC) is a naturally occurring component of mammalian genomic DNA and is thought to be the sixth base of DNA [1]. HM-cytosine is an intermediate metabolite for demethylation of active DNA [2]. HM-cytosine is an ep

HM-cytosine

HM-cytosine

🥰Excellent
Purity: 99.49%
Catalog No. T35363Alias 5-Hydroxymethylcytosine, 5hmCCas No. 1123-95-1
HM-cytosine (5hmC) is a naturally occurring component of mammalian genomic DNA and is thought to be the sixth base of DNA [1]. HM-cytosine is an intermediate metabolite for demethylation of active DNA [2]. HM-cytosine is an ep
Pack SizePriceAvailabilityQuantity
1 mg$40In Stock
2 mg$57In Stock
5 mg$94In Stock
10 mg$147In Stock
25 mg$289In Stock
50 mg$429In Stock
100 mg$622In Stock
1 mL x 10 mM (in DMSO)$77In Stock
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Purity:99.49%
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Product Introduction

Bioactivity
Description
HM-cytosine (5hmC) is a naturally occurring component of mammalian genomic DNA and is thought to be the sixth base of DNA [1]. HM-cytosine is an intermediate metabolite for demethylation of active DNA [2]. HM-cytosine is an ep
Alias5-Hydroxymethylcytosine, 5hmC
Chemical Properties
Molecular Weight141.13
FormulaC5H7N3O2
Cas No.1123-95-1
SmilesNC1=C(CO)C=NC(O)=N1
Relative Density.1.3818 g/cm3 (Estimated)
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 5 mg/mL (35.43 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM7.0857 mL35.4283 mL70.8567 mL354.2833 mL
5 mM1.4171 mL7.0857 mL14.1713 mL70.8567 mL
10 mM0.7086 mL3.5428 mL7.0857 mL35.4283 mL
20 mM0.3543 mL1.7714 mL3.5428 mL17.7142 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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